Chloramphenicol Palmitate is a broad-range antibiotic prescribed by veterinarians to treat bacterial infections and some single-celled pathogenic organisms in dogs and cats.
Treating Bacterial Infections With Chloramphenicol Palmitate
Chloramphenicol Palmitate is typically used for the treatment of skin infections, wound infections, bone infections, intestinal tract infections and pneumonia in dogs and cats.
Since it has the ability to pass deeply through cell membranes and other purulent material to attack bacteria residing in places other antibiotics cannot reach, Chloramphenicol Palmitate is also a preferred method of treatment for infections of the nervous system, like meningitis and encephalitis, as well as certain tick-transmitted diseases like Rocky Mountain Spotted Fever.
Chloramphenicol Palmitate Precautions and Drug Interactions
Chloramphenicol Palmitate should not be prescribed to an animal patient with a known allergy to the drug or animals that are pregnant, as it has been shown to pass into the milk. Similarly, this drug should not be administered to very young animals or those suffering from abnormal bone marrow, liver or kidney failure or non-regenerative anemia.
Chloramphenicol Palmitate has the potential to interact with other medications, so it is crucial to inform the veterinarian of any other drugs the animal may be taking. Chloramphenicol Palmitate may cause interactions when administered alongside drugs like phenobarbital, primidone, tylosin, phenytoin, and cyclophosphamide or with other antibiotics like amoxicillin, clindamycin or erythromycin. The medication can also interfere with vaccinations.
Possible Side Effects of Chloramphenicol Palmitate
While Chloramphenicol Palmitate is safe and effective for use in both dogs and cats, the feline population is more susceptible to possible reactions and should be monitored closely.
The most common possible side effects of Chloramphenicol Palmitate include vomiting, diarrhea and lack of appetite. If the drug is administered in high doses over a prolonged period of time, a condition called blood dyscrasias can develop, in which the body produces abnormal blood cells or normal blood cell development is halted. This condition is most common in cats.
Unlike Chloramphenicol, which is available in a wide range of formulations, Chloramphenicol Palmitate is only available in an oral tablet formulation. A prescription from a licensed veterinarian is required to obtain this medication.
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Author: Giano Panzarella