Benefits and Uses of Diazepam

Potassium Bromide for Veterinary Use

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Posts Tagged ‘sedative’

Benefits and Uses of Diazepam

Saturday, September 12th, 2009

A benzodiazepine tranquilizer, diazepam is used in veterinary medicine to sedate, reduce anxiety, promote behavioral changes or induce muscle relaxation. Diazepam is also an anticonvulsant and can be administered to some species to stimulate appetite.

Diazepam and Veterinary Compounding

In veterinary medicine, diazepam is commonly prescribed for dogs, cats, reptiles, sheep, cattle, horses, goats and swine. Depending on the needs of the individual patient, veterinary compounding can alter the form of the drug for oral, intravenous, rectal or intramuscular administration.

Veterinary Medicine — Diazepam Uses for Dogs and Cats

Diazepam is commonly administered as a sedative, muscle relaxant, anticonvulsant or anti-anxiety medication for dogs and cats. It may be given alone or combined in veterinary compounding in order to pointedly address individual dosage needs.

Diazepam is also used in the treatment of behavioral problems, such as aggression, excessive grooming, territorial spraying and terror caused by loud noises. When treating dogs for aggression, it is possible that diazepam can produce a reverse outcome, causing amplification rather than suppression of aggressive behaviors.

As an anticonvulsant, diazepam may be used in veterinary medicine for the treatment of seizures, whether due to toxic shock or status epilepticus. However, since dogs develop a tolerance rather quickly, diazepam is not typically selected for the continued management of seizures.

Veterinary Medicine — Diazepam and Horses

While not an analgesic, diazepam is commonly administered to sedate horses prior to surgical procedures. In adult horses, diazepam is often paired with another medication in to produce the necessary level of sedation.

Diazepam can also be administered to horses as an anticonvulsant, whether alone or as part of an amalgamation of other medications. It can also assist with breeding behaviors, particularly for withdrawn stallions.

Diazepam and Potential Side Effects

Common side effects may include impaired coordination and lethargy. Aggression, excitement or marked behavioral changes are unusual side effects. In addition, while a rarity, hepatic toxicity has also been reported in some cats.

Be sure to thoroughly discuss drug interactions and additional precautions with a specialist in veterinary medicine before using diazepam for treatment.

Potassium Bromide for Veterinary Use

Saturday, September 12th, 2009

Potassium bromide is a water-soluble ionic salt compound. Potassium bromide, or KBr, is usually produced via a reaction of a bromide of iron with potassium carbonate. The brand name for KBr is Dibro-Be mono.

In 1857, Sir Charles Locock discovered the anticonvulsant and sedative traits of potassium bromide and began treating his patients. From that point, potassium bromide became a choice treatment for humans with epileptic seizures and nervous disorders until the 1912 discovery of Phenobarbital.

The introduction of Phenobarbital considerably decreased the popularity of potassium bromide in treating humans with epileptic seizures. As a result, potassium bromide is not approved by the U.S. Food and Drug Administration.

Potassium Bromide and Veterinary Medicine

Potassium bromide is often prescribed in veterinary medicine for the effective treatment of epileptic seizures in dogs. Depending on the needs of the individual patient, potassium bromide may be the sole form of treatment or used in correlation with Phenobarbital.

Potassium bromide therapy is a rarity among the feline species, as treatment may substantially increase the risk of lung inflammation. Alternative therapies are often explored for cats, such as Diazepam or Phenobarbital, before introducing potassium bromide.

In veterinary medicine, potassium bromide typically comes in a liquid of capsule form. Since it can take three to four months to reach a steady bromide blood level, patients often receive a high dosage at the onset of treatment.

Veterinary Medicine — Potassium Bromide and Potential Side Effects

Many experts in veterinary medicine consider potassium bromide to be equally, if not more effective than Phenobarbital in treating dogs for seizures. However, as with virtually all medications, the possibility of side effects does exist.

Among other potential side effects, patients taking potassium bromide may experience appetite loss, nausea, frequent urination, thirst and drowsiness, especially when treatment is initiated with a high dosage. Coughing is another possible side effect. In such cases, potassium bromide treatment may be halted.

Potassium bromide should be administered with food. Be sure to consult with a licensed specialist in veterinary medicine to arrive at the best possible treatment.