Cidofovir is an anti-viral nucleoside analogue used in veterinary medicine primarily for the treatment of feline herpes virus (FHV-1) and the ocular disorders that develop as a result of the disease.

Cidofovir for Feline herpes

Treating Cats With Cidofovir

In veterinary medicine, the most common formulation of Cidofovir is the ophthalmic solution or ointment. The aforementioned formulation is used to treat FHV-1-associated conjunctivitis and keratitis. Veterinarians commonly prescribe Cidofovir for FHV-1 because it is a very powerful, full spectrum drug with a long intracellular half-life that allows for less-frequent administrations.

Possible Side Effects of Cidofovir

Since Cidofovir is a powerful medication, some animals may experience side effects after it is administered. Research shows that the severity of possible side effects is directly related to the species of animal being treated and the concentration of the solution. Potential, but rare, side effects include ocular hypotonia, obstruction of the nasolacrimal duct and superficial punctate keratitis.

Cidofovir Precautions and Drug Interactions

Before Cidofovir is prescribed to treat feline acute conjunctivitis, it should be ruled out that bacteria such as Chlamydophila felis or Mycoplasma felis are not causing the condition.

If the animal patient is currently taking other medications, the treating veterinarian should be notified, as Cidofovir may interact with one or more drugs. For instance, topical ophthalmic corticosteroids have a tendency to decrease the anti-viral properties of Cidofovir, rendering the medication less effective.


Author: Giano Panzarella