Estradiol Benzoate Is a Form of Estrogen

Estradiol Benzoate is a form of estrogen, the female sex hormone that is produced in the ovaries. In veterinary medicine, Estradiol Benzoate is used to initiate follicle turnover in postpartum beef cattle. It is also used to promote growth and feed efficiency in heifers weighing 400 lbs or more, and as a hormone replacement for horses.

estrogen in cattle

Estradiol Benzoate and the Beef Cattle Industry

As artificial insemination becomes more and more commonplace in the beef cattle industry, producers are continuously looking for estrus or ovulation control systems that will provide them with more consistent results. Injection of progesterone-like compounds, or progestagens, has long been the standard for preventing estrus. However, cows injected with Estradiol Benzoate have nearly double the pregnancy rates than cows not treated with the medication.

How Is Estradiol Benzoate Supplied?

Estradiol Benzoate is available with a prescription from a veterinarian as an injectable formulation.

Estradiol Benzoate Considerations and Precautions

Estradiol Benzoate should not be prescribed to animals with a known allergy or hypersensitivity to it. It should also be avoided in pregnant or nursing animals and those suffering from blood clotting problems, cancer of the uterus, heart problems, liver disease, kidney disease, breast cancer, bone cancer, pancreatitis, and endometriosis.

It is important to address the current drug regimen of the animal patient with the veterinarian first, in order to prevent a potentially hazardous drug interaction.

Possible Side Effects of Estradiol Benzoate

Estradiol Benzoate may cause some animals to experience particular side effects. The most common potential side effects include nausea and weight gain.

An animal experiencing difficulty breathing, swelling of the lips, tongue or face or skin rash or hives, may be experiencing an allergic reaction to the medication. In such cases, contact the veterinarian immediately.

Author: Giano Panzarella