Mirtazapine is a tetracyclic anti-depressant that is prescribed by veterinarians to treat a wide range of conditions, from behavioral problems to loss of appetite in cats.

Veterinary Uses for Mirtazapine

Mirtazapine is most commonly used as an appetite stimulant for dogs and cats that are refusing to eat. It is also prescribed for the long-term treatment of various patients who are experiencing nausea, vomiting, and anorexia .

Other uses for mirtazapine include treating behavioral problems like separation anxiety, urine spraying and insomnia.

How Is Mirtazapine Supplied?

Mirtazapine is available from compounding pharmacies in varying strengths of oral and topical formulations. The dosage, formulation and frequency of administration are determined according to what the drug is being used to treat and the type and size of animal receiving the treatment.

Since this medication is an anti-depressant, abrupt cessation of the drug is not recommended.  The animal should be weaned off of mirtazapine over an acceptable period of time.

Mirtazapine Precautions

Mirtazapine should not be prescribed or administered to a patient that is hypersensitive or allergic to the medication. It should also be used with caution whenever the animal is taking other medications, as it may interact with other drugs. Such drugs include tramadol and monoamine oxidase inhibitors.

Side Effects of Mirtazapine

Mirtazapine is generally well tolerated in dogs and cats, although trials are lacking.

Common side effects include drowsiness, sedation, low blood pressure, and increased heart rate.

If the animal experiences breathing difficulties, hives or swelling of the lips, tongue or face, then an allergic reaction to the drug may be the case and the veterinarian should be contacted immediately.

Author: Giano Panzarella

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